Table 6.
Results for changes observed in the liver of animals in each experimental group.
| Variable | Experimental Group | ||||
|---|---|---|---|---|---|
| SHAM SALINE | HFD SALINE | AGE 50 | AGE 100 | AGE 150 | |
| Liver Changes | |||||
| Steatosis (p = 0.881) | |||||
| < 5% | 54.5 (5) | 36.4 (4) | 54.5 (6) | 60.0 (6) | 54.5 (6) |
| 5 to 33% | 36.4 (4) | 36.4 (4) | 36.4 (4) | 10.0 (1) | 36.4 (4) |
| 34 to 66% | 9.1 (1) | 18.2 (2) | 9.1 (1) | 20.0 (2) | 9.1 (1) |
| >66% | 0.0 (0) | 9.1 (1) | 0.0 (0) | 10.0 (1) | 0.0 (0) |
| Microvesicular steatosis (p = 0.501) | |||||
| Absent | 45.5 (5) | 18.2 (2) | 54.5 (6) | 40.0 (4) | 36.4 (4) |
| Present | 54.5 (6) | 81.8 (9) | 45.5 (5) | 60.0 (6) | 63.6 (7) |
| Lobular inflammation (p = 0.919) | |||||
| Absent | 63.6 (7) | 72.7 (8) | 81.8 (9) | 70.7 (7) | 72.7 (8) |
| <1 focus/field | 36.4 (4) | 27.3 (3) | 18.2 (2) | 30.0 (3) | 27.3 (3) |
| 2–4 focuses/field | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) |
| > 4 focuses/field | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) |
| Ballooning (p = 0.91) | |||||
| Absent | 72.7 (8) | 36.4 (4) | 81.8 (9) | 70.7 (7) | 72.7 (8) |
| Few cells | 27.3 (3) | 63.6 (7) | 18.2 (2) | 30.0 (3) | 27.3 (3) |
| Many cells | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) |
| Mallory’s hyaline (p = 0.91) | |||||
| Absent | 100.0 (11) | 100.0 (11) | 100.0 (11) | 100.0 (10) | 90.9 (10) |
| Present | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) | 9.1 (1) |
| Apoptosis | |||||
| Absent | 100.0 (11) | 100.0 (11) | 100.0 (11) | 100.0 (10) | 100.0 (11) |
| Present | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) |
| Glycogenate nucleus (p = 0.408) | |||||
| None/rare | 100.0 (11) | 100.0 (11) | 100.0 (11) | 100.0 (10) | 90.9 (10) |
| Some | 0.0 (0) | 0.0 (0) | 0.0 (0) | 0.0 (0) | 9.1 (1) |
Data presented as relative frequency (absolute frequency). Value of p in the chi-square test.