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. 2019 May 16;18(8):1683–1699. doi: 10.1074/mcp.RA118.001169

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© 2019 Tang et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Fig. 4. — The strategy proposed in this study to discover the manipulation chains of simultaneously improved precision and accuracy based on the benchmarks from Table II, study 11. First, clustering analyses among chains across five quantification tools were conducted for (A) precision and (B) accuracy. Second, a two-dimensional scatter plot (C) was drawn to show the ranks of each manipulation chain (represented by a gray dot) collectively determined by precision (horizontal axis) and accuracy (vertical axis). The pink, violet, and green areas in C denoted the chains of good precision (A1+A2+A3 in A), good accuracy (A1+A2 in B), and good performance for both, respectively. As a result, 91 chains (within the green region of C) were found to perform well under both criteria (precision and accuracy).