Table 2.
Startup | Follow-Up | Treatment × Time Interaction b | |||||
---|---|---|---|---|---|---|---|
Active | Placebo | Active | Placebo | Active | Placebo | p Value | |
MMSE | 27.5 ± 2.2 | 27.0 ± 2.1 | 27.1 ± 2.5 | 26.0 ± 3.4 | −0.4 ± 1.6 | −1.0 ± 1.8 | 0.252 |
gloCDR | 0.5 | 0.5 | 0.38 ± 0.2 | 0.48 ± 0.2 | −0.12 ± 0.22 | −0.02 ± 0.18 | 0.0231 |
CDRsob | 0.82 ± 0.45 | 1.04 ± 0.53 | 0.80 ± 0.5 | 1.12 ± 0.77 | −0.02 ± 0.51 | 0.12 ± 0.79 | 0.583 |
WMS-1 | 7.8 ± 4.4 | 7.0 ± 4.5 | 9.1 ± 4.4 | 8.2 ± 5.7 | 1.2 ± 2.8 | 1.2 ± 3.1 | 0.591 |
WMS-2 | 5.3 ± 4.4 | 5.6 ± 4.6 | 6.7 ± 5.2 | 6.4 ± 6.1 | 1.4 ± 3.0 | 0.7 ± 3.0 | 0.975 |
ADAS | 12.3 ± 7.4 | 15.5 ± 7.6 | 13.0 ± 8.5 | 15.4 ± 8.6 | 0.8 ± 4.4 | −0.2 ± 4.7 | 0.320 |
GDS | 2.5 ± 1.9 | 2.5 ± 2.4 | 2.6 ± 2.9 | 2.6 ± 2.1 | 0.1 ± 2.7 | 0.1 ± 2.0 | 0.943 |
a Data are shown in mean ± Standard Deviation. b The change between start-up and follow-up.