Table 2.

Classification of the risk groups of prostate cancer [83].

Risk Group	Clinical Stage	PSA (ng/mL)	Gleason Score	Biopsy Criteria
Low	T1a or T1c	<10	2–6	Unilateral or <50% of core involved
Intermediate	T1b, T1c, or T2a	<10	3 + 4 = 7	Bilateral
High	T1b, T1c, T2b, or T3	10–20	4 + 3 = 7	>50% of core involved or perineural invasion or ductal differentiation
Very high	T4	>20	8–10	Lymphovascular invasion or neuroendocrine differentiation