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. 2019 Aug 5;9:11304. doi: 10.1038/s41598-019-47839-5

Figure 2.

Figure 2

Effects of known associated factors on the trajectories in standardized scores (z-scores) of fetal anthropometric values during gestation. Changes in fetal anthropometric standardized scores (z-scores) of subgroups classified by known factors (such as fetal sex, maternal height, pre-pregnancy BMI, and parity) during gestation are shown. Color codes, showing distinct subgroups for each factor, are indicated in the bottom left. All weekly values (dots) with mean (solid lines) and ±1 SD (dashed lines) of z-scores are shown. Linear mixed models were used to compare groups with the Bonferroni method for multiple testing correction. Asterisk (*) indicates the significant interaction between time and the given factor for each anthropometric value. (Effect size > 0.01 and p-value < 2.7 × 10−4). EFW, estimated fetal weight; BPD, biparietal diameter; FL, femur length; AC, abdominal circumference; BMI, body mass index.