Table 3.

(Experiment 1). (a) Quintiles based on the 30’-OGTT for 255 3-week old male Nile rats after being housed with littermates immediately upon weaning for either 2 or 4 weeks and fed a hiCHO diet (Diet 73MBS, NR Study 129); (b) Quintiles based on the 30’-OGTT for 247 3-week old female Nile rats after being housed with littermates immediately upon weaning for either 2 or 4 weeks and fed a hiCHO diet (Diet 73MBS, NR Study 129).

CHO:Fat:Protein%energy	Diet 73MBS (70:10:20) *					Diet 73MBS (70:10:20) *
(a) Males
	Housed together for 2 weeks (n = 165)					Housed together for 4 weeks (n = 90)
Quintile	1	2	3	4	5	1	2	3	4	5
30’-OGTT range (mg/dl)	(59–61)	(59–161)	(214–241)	(245–292)	(296–435)	(44–98)	(103–149)	(150–192)	(193–257)	(260–525)
Fasting Body Weight (g)	56 ± 9abc	57 ± 7	60 ± 10a	61 ± 7b	61 ± 7c	67 ± 11	65 ± 7ab	67 ± 7	71 ± 10a	72 ± 9b
	Oral Glucose Tolerance Test (mg/dl) after 2 weeks					Oral Glucose Tolerance Test (mg/dl) after 4 weeks
FBG, 0 min	55 ± 20a	54 ± 19b	55 ± 16c	62 ± 23	65 ± 21abc	41 ± 10ab	51 ± 27c	47 ± 11d	59 ± 23a	67 ± 34bcd
30 min	121 ± 28abcd	193 ± 15aefg	227 ± 9behi	270 ± 14cfhj	337 ± 37dgij	82 ± 15abcd	127 ± 15aefg	174 ± 13behi	236 ± 17cfhj	336 ± 79dgij
(b) Females
	Housed together for 2 weeks (n = 138)					Housed together for 4 weeks (n = 109)
Quintile	1	2	3	4	5	1	2	3	4	5
30’-OGTT range (mg/dl)	(86–138)	(140–175)	(178–216)	(216–270)	(272–427)	(40–105)	(106–139)	(141–174)	(175–216)	(223–398)
Fasting Body Weight (g)	44 ± 7ab	47 ± 7	46 ± 6c	51 ± 8ac	49 ± 8b	47 ± 9a	48 ± 10b	51 ± 12	55 ± 11ab	51 ± 10
	Oral Glucose Tolerance Test (mg/dl) after 2 weeks					Oral Glucose Tolerance Test (mg/dl) after 4 weeks
FBG, 0 min	56 ± 18a	58 ± 17b	61 ± 18c	68 ± 20	74 ± 34abc	52 ± 16ab	60 ± 21	68 ± 40a	64 ± 15	76 ± 27b
30 min	111 ± 14abcd	159 ± 11aefg	197 ± 11behi	246 ± 18cfhj	318 ± 47dhij	82 ± 18abcd	124 ± 9aefg	156 ± 11behi	196 ± 15cfhj	279 ± 43dgij

* Represents Diet 73MBS, CHO:Fat:Protein %energy with GLoad of 259/2000 kcal; 4.0 kcal/g dry diet.