. 2019 Jul 6;11(7):1538. doi: 10.3390/nu11071538

Table 6.

(Experiment 4). Quintiles of RBG along with diabetes metagenetic profile for 30 female Nile Rats (3 weeks old) fed semipurified hiCHO Diet 133 (60:20:20)* for 3 weeks, then subdivided into ’resistant’ or ’susceptible’ quintiles based on RBG <75 mg/dl>, respectively (NR Studies 133, 133(2), 139).

Diet (CHO:Fat:Protein %energy)	Diet 133 (60:20:20) *
Quintiles by RBG	Q1	Q2	Q3	Q4	Q5
T2DM ’genetic permissiveness’ ranked by quintiles	Resistant	Resistant	Susceptible	Susceptible	Susceptible
*n =*	6	6	6	6	6
RBG (range) after 3 weeks (mg/dl)	(51–64)	(65–74)	(74–80)	(80–88)	(89–215)
Ave after 3 weeks	60 ± 5^a	69 ± 4^b	77 ± 3^c	82 ± 3^d	123 ± 49^abcd
	Body Weight (g)
Initial (3 weeks of age)	27 ± 3	30 ± 6	30 ± 4	28 ± 4	28 ± 2
after 3 weeks on diet	57 ± 9	57 ± 5	61 ± 4	59 ± 4	56 ± 10
	Oral Glucose Tolerance Test (mg/dl) after 3 weeks
FBG, 0 min	64 ± 25	51 ± 11	51 ± 11	69 ± 25	70 ± 18
30 min	159 ± 48^a	193 ± 67	243 ± 56^a	168 ± 41	225 ± 109
	Organ weight (%BW)
Liver	3.55 ± 0.52	3.37 ± 0.34	3.88 ± 0.6^a	3.23 ± 0.29^ab	3.93 ± 0.56^b
Kidney	0.7 ± 0.09	0.73 ± 0.06	0.67 ± 0.06	0.66 ± 0.05	0.67 ± 0.09
Cecum	1.42 ± 0.16	1.61 ± 0.53	1.44 ± 0.26	1.36 ± 0.36	1.56 ± 0.4
	Adipose
Epididymal	1.97 ± 0.56	2.16 ± 0.84	2.33 ± 0.48	2.54 ± 0.49	2.06 ± 0.6
Perirenal	1.16 ± 0.6	0.98 ± 0.27^a	1.26 ± 0.47	1.5 ± 0.46^a	1.25 ± 0.27
Brown fat	2.07 ± 0.58	2.16 ± 0.18	2.47 ± 0.45	2.42 ± 0.27	2.24 ± 0.62
Total fat	4.34 ± 1.64	4.65 ± 2.04	4.73 ± 2.04	5.65 ± 1.66	4.65 ± 1.72
Carcass (%BW)	73 ± 10	77 ± 1	76 ± 1	76 ± 1	77 ± 2
Length (cm)	11.4 ± 0.4	11.5 ± 0.5	11.9 ± 0.2	11.6 ± 0.4	11.5 ± 0.7
Body Mass Index (kg/m²) based on 3 week FBW	4.42 ± 0.46	4.32 ± 0.34	4.31 ± 0.27	4.38 ± 0.52	4.24 ± 0.54

* Represents CHO:Fat:Protein % energy with GLoad 224/2000kcal; 4.2 kcal/g dry diet. Values are mean ± SD. ^{a, b} Means in a row sharing common superscripts are significantly different (P < 0.05) by one-way ANOVA and Fisher’s PLSD test. ^# n = 6 per Quintile, total 30 rats.