Table 2.
Parameters related to the menopausal symptoms.
| Parameters | OVX (n = 10) |
OVX-OA (n = 10) |
OVX-OA-RARF-L (n = 10) |
OVX-OA-RARF-H, (n = 10) |
Sham (n = 10) |
|---|---|---|---|---|---|
| Uterine weight (g) | 0.18 ± 0.06 b | 0.17 ± 0.06 b | 0.18 ± 0.05 b | 0.18 ± 0.06 b | 0.51 ± 0.08 a |
| Serum 17β-estradiol levels (pg/mL) | 1.7 ± 0.7 b | 1.6 ± 0.6 b | 1.7 ± 0.6 b | 1.6 ± 0.7 b | 7.2 ± 1.0 a |
| Skin temperature (°C) at 8 weeks | 29.4 ± 0.05 a | 29.3 ± 0.05 a | 28.9 ± 0.03 ab | 29.0 ± 0.03 ab | 28.6 ± 0.08 b |
| Skin temperature (°C) at 11 weeks | 29.5 ± 0.09 a | 29.4 ± 0.15 a | 28.9 ± 0.09 ab | 29.0 ± 0.09 ab | 28.4 ± 0.08 b |
Ovariectomized rats were divided into four groups: (1) monoiodoacetate (MIA) injection into the knee joint and fed a high fat diet containing 0.23% rice+0.018% AFR diet (OVX-OA-RAFR-L), (2) MIA injection into the knee joint and fed a high fat diet containing 0.69% rice+0.053% AFR diet (OVX-OA-RAFR-H), (3) MIA injection into the knee joint and fed a high fat diet added 0.053% cellulose (OVX-OA), or (4) saline injection into the knee joint and fed a high fat diet containing 0.053% cellulose (OVX). Sham rats had the same diet as control and saline injection (Sham; normal-control). At the beginning of the 8th week, an articular injection of monoiodoacetate into the right knee was performed in all OVX groups except the normal-control group and the assigned diets were provided for an additional 3 weeks. Values are mean ± SD. a,b Values on the same row with different superscripts were significantly different among groups by Tukey test at p < 0.05.