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. 2019 Aug 5;20:175. doi: 10.1186/s12931-019-1144-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — a Reconstructed spatial distribution images of the SP-C analog in the lungs of surfactant-treated (SF) and untreated control (C) animals. b Boxplots showing the difference of MSI-derived parameters (the log10 average intensity of ion inside the lung tissue section, Avg_log₁₀_I; and the absolute signal of the ion in the lung section from those pixels with a signal above the noise level, Σ_log₁₀_I) in control (Ctrl) and surfactant-treated animals. Quantification results for SP-C analog (c). Blue, horizontal lines in quantification charts identify the 95% confidence intervals