Table 3.
Correlations between Fatigue Severity Scale and preference-based measures
| FSS total score and PBM dimensions | rho | Observations |
|---|---|---|
| EQ-5D versus FSS total score | ||
| Mobility | 0.423 | 1035 |
| Self-care | 0.385 | 1048 |
| Usual activities | 0.524 | 1051 |
| Pain/Discomfort | 0.361 | 1047 |
| Anxiety/Depression | 0.292 | 1049 |
| SF-6D versus FSS total score | ||
| Physical functioning | 0.547 | 649 |
| Role limitations | 0.424 | 645 |
| Social functioning | 0.530 | 644 |
| Pain | 0.429 | 642 |
| Mental health | 0.324 | 648 |
| Vitality | 0.615 | 654 |
| MSIS-8D versus FSS total score | ||
| Physically demanding tasks | 0.585 | 656 |
| Social and leisure activities | 0.560 | 652 |
| Mobility (being stuck at home) | 0.489 | 656 |
| Work or other daily activities | 0.558 | 655 |
| Feeling mentally fatigued | 0.582 | 656 |
| Feeling irritable, impatient or short-tempered | 0.377 | 654 |
| Problems concentrating | 0.450 | 654 |
| Feeling depressed | 0.320 | 653 |
| EQ-5D versus FSS item | ||
| 1 My motivation is lower | −0.285 | 1040 |
| 2 Exercise brings on my fatigue | − 0.382 | 1038 |
| 3 I am easily fatigued | − 0.464 | 1040 |
| 4 Interferes with physical functioning | −0.471 | 1033 |
| 5 Causes frequent problems for me | −0.498 | 1039 |
| 6 Prevents sustained physical functioning | −0.527 | 1040 |
| 7 Interferes with duties and responsibilities | −0.536 | 1038 |
| 8 Among my most disabling symptoms | −0.336 | 1035 |
| 9 Interferes with work, family or social life | −0.482 | 1039 |
| SF-6D versus FSS item | ||
| 1 My motivation is lower | −0.400 | 614 |
| 2 Exercise brings on my fatigue | − 0.409 | 614 |
| 3 I am easily fatigued | −0.545 | 614 |
| 4 Interferes with physical functioning | −0.541 | 612 |
| 5 Causes frequent problems for me | −0.585 | 614 |
| 6 Prevents sustained physical functioning | −0.575 | 614 |
| 7 Interferes with duties and responsibilities | −0.623 | 613 |
| 8 Among my most disabling symptoms | −0.455 | 610 |
| 9 Interferes with work, family or social life | −0.603 | 614 |
| MSIS-8D versus FSS item | ||
| 1 My motivation is lower | −0.387 | 659 |
| 2 Exercise brings on my fatigue | −0.423 | 659 |
| 3 I am easily fatigued | −0.560 | 659 |
| 4 Interferes with physical functioning | −0.554 | 656 |
| 5 Causes frequent problems for me | −0.615 | 659 |
| 6 Prevents sustained physical functioning | −0.606 | 660 |
| 7 Interferes with duties and responsibilities | −0.637 | 660 |
| 8 Among my most disabling symptoms | −0.428 | 656 |
| 9 Interferes with work, family or social life | −0.596 | 659 |
All coefficients significant at p < 0.0001
PBM preference-based measure, FSS Fatigue Severity Scale, EQ-5D EuroQoL EQ-5D-3L, SF-6D Short-Form 6D, MSIS-8D Multiple Sclerosis Impact Scale – Eight Dimensions