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Secretome of ASCs. a During 48 h culture, ASCs secreted into the culture medium mainly IL-6 and small amounts of RANTES, osteoprotegerin, MCP-1, and GRO particles. The graph shows an averaged level of secreted cytokines by ASCs (n = 3). b The secretion of the most abundant cytokine—IL-6—was donor-specific, and the medium formulation did not influence its secretion. The amount of secreted IL-6 based on the ELISA assay (n = 4) performed in respective cell culture
