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. 2019 Aug 5;16:162. doi: 10.1186/s12974-019-1551-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Multiple sclerosis risk-associated amino acid positions of the HLA genes in three-dimensional structure models. HLA amino acid positions with significant MS risk in HLA-DQ molecules. The protein structure is based on Protein Data Bank (PDB) entries 1jk8 and prepared using UCSF Chimera (version 1.7). Residues at the amino acid positions with significant MS risk is highlighted in red