Table 4.

HLA association analysis with the clinical course of MS

	Number of patients	EDSS	P (Student’s t)
A
HLA-DRB1*15:01 positive	18	3.08	0.990
HLA-DRB1*15:01 negative	27	3.09
HLA-DQB1*06:02 positive	17	3.41	0.472
HLA-DQB1*06:02 negative	28	2.89
HLA-B*15:01 positive	15	4.20	0.098
HLA-B*15:01 negative	30	2.53
HLA-B*39:01 positive	11	3.50	0.504
HLA-B*39:01 negative	34	2.96
	Number of patients	Age of onset	P (Student’s t)
B
HLA-DRB1*15:01 positive	18	33.3	0.618
HLA-DRB1*15:01 negative	27	35.0
HLA-DQB1*06:02 positive	17	33.0	0.545
HLA-DQB1*06:02 negative	28	35.1
HLA-B*15:01 positive	15	35.1	0.752
HLA-B*15:01 negative	30	33.9
HLA-B*39:01 positive	11	30.0	0.142
HLA-B*39:01 negative	34	35.7

*Student’s t test was used for association analysis