Table 5.
Level of genotyping | % Herd genotyping | Predicted number of homozygous individuals per 100 matings (aa) | |||||
---|---|---|---|---|---|---|---|
A | B | C | |||||
Base | 0 | 0.70 (0.000) | 12.45 (0.000) | 15.22 (0.000) | |||
Strategyb | 1 | 2 | 1 | 2 | 1 | 2 | |
Low | 10 | 0.70 (0.003) | 0 (0.000) | 9.11 (0.003) | 8.17 (0.003) | 12.42 (0.003) | 6.77 (0.003) |
20 | 0.70 (0.003) | 0 (0.000) | 7.43 (0.003) | 7.48 (0.002) | 6.06 (0.003) | 5.97 (0.003) | |
30 | 0.70 (0.003) | 0 (0.000) | 6.08 (0.003) | 6.47 (0.003) | 6.05 (0.003) | 5.92 (0.003) | |
Intermediate | 40 | 0.70 (0.003) | 0 (0.000) | 5.21 (0.003) | 5.69 (0.003) | 4.80 (0.003) | 4.87 (0.002) |
50 | 0.70 (0.003) | 0 (0.000) | 5.05 (0.003) | 5.12 (0.002) | 4.75 (0.003) | 3.87 (0.003) | |
60 | 0.70 (0.003) | 0 (0.000) | 4.58 (0.003) | 4.59 (0.002) | 4.7 5(0.003) | 3.87 (0.003) | |
High | 70 | 0.35 (0.003) | 0 (0.000) | 4.06 (0.003) | 4.09 (0.002) | 4.75 (0.003) | 3.84 (0.003) |
80 | 0.35 (0.003) | 0 (0.000) | 4.01 (0.002) | 3.53 (0.002) | 4.35 (0.003) | 3.23 (0.003) | |
90 | 0.35 (0.002) | 0 (0.000) | 3.68 (0.003) | 3.23 (0.002) | 4.35 (0.002) | 1.89 (0.001) | |
100 | 0.35 (0.003) | 0 (0.000) | 3.61 (0.003) | 2.89 (0.002) | 4.25 (0.003) | 1.83 (0.002) |
aScenario A (7 loci with high-frequency LOF alleles), scenario B (76 loci with low-frequency LOF alleles), and scenario C (50 with high- and low-frequency loci)
bSelection against carrier parents (strategy 1) and selection and mate allocation to avoid homozygous offspring (strategy 2)