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. 2019 Aug 6;51:36. doi: 10.1186/s12711-019-0477-3

Table 6.

Average sire index value ($MB) and genetic load scores (GLS) for different percentages of herd genotyped in three scenariosa given two selection strategiesb

Scenarioa Strategyb Weightings against selection strategies
0 0.001 0.01 0.1 1 10 100
A 1 $MB 141.03 141.03 141.03 140.98 140.61 141.03 141.03
GLS 0.049 0.027 0.027 0.024 0.005 0 0
2 $MB 141.03 141.03 141.03 141.03 141.03 141.03 141.03
GLS 0.049 0.049 0.049 0.049 0.049 0.049 0.049
B 1 $MB 141.03 141.03 140.97 140.75 130.57 86.74 86.50
GLS 0.287 0.287 0.281 0.265 0.157 0 0
2 $MB 141.03 141.03 141.03 141.03 132.21 118.97 115.34
GLS 0.287 0.284 0.284 0.259 0.177 0.131 0.113
C 1 $MB 141.03 141.03 141.03 140.80 133.75 84.90 84.90
GLS 0.333 0.333 0.332 0.298 0.167 0.012 0.012
2 $MB 141.03 141.03 140.93 138.81 131.60 116.11 110.06
GLS 0.333 0.333 0.333 0.257 0.163 0.100 0.080

In italic characters = the profit maximizing weighting for a given scenario and breeding strategy

aScenario A (7 loci with high-frequency LOF alleles), scenario B (76 loci with low-frequency LOF alleles), and scenario C (50 with high- and low-frequency loci)

bSelection against carrier parents (strategy 1) and selection and mate allocation to avoid homozygous offspring (strategy 2)