Table 1.
Baseline characteristics of peritoneal dialysis patients and hemodialysis patients
Characteristics | PD | HD | p |
---|---|---|---|
Number | 110 | 110 | |
Median age (year) | 57.5±14.4 | 56.0±14.7 | 0.263 |
Gender, n (%) | |||
Male | 53 (48.2) | 53 (48.2) | 0.844 |
Female | 58 (52.8) | 58 (52.8) | |
Dialysis vintage, months | 14.5 (9, 31) | 46 (28, 73) | < 0.001 |
CMV exposure (%) | 92.8 | 91.5 | 0.88 |
Underlying kidney disease, n (%) | |||
Chronic glomerulonephritis | 33 (24.8) | 53 (47.7) | 0.006 |
Hypertensive nephropathy | 23 (17.3) | 11 (9.9) | 0.025 |
Diabetic kidney disease | 21 (15.8) | 22 (19.8) | 0.865 |
Kidney stone disease | 3 (2.2) | 2 (1.8) | 0.651 |
Polycystic kidney disease | 5 (3.8) | 4 (3.6) | 0.734 |
Others | 31 (23.3) | 14 (12.6) | 0.002 |
Unknown | 17 (12.8) | 5 (4.5) | 0.007 |
Laboratory parameters | |||
WBC (× 109/L) | 6.4 (5.2, 7.7) | 6.3 (5.1, 7.88) | 0.134 |
Neutrophil (× 109/L) | 4.2 (3.3, 5.0) | 4.1 (3.3, 5.7) | 0.925 |
Lymphocyte (× 109/L) | 1.5 (1.0, 1.9) | 1.2 (1.0, 1.7) | 0.126 |
Monocyte (× 109/L) | 8.7 (7.2, 10.1) | 8.0 (6.7, 9.4) | 0.108 |
T cell (× 106/L) | 1075.5 (769.0, 1345.0) | 800.0 (609.0, 992.5) | < 0.001 |
CD4 T cell (× 106/L) | 638.0 (486.0, 798.5) | 452.0 (361.0, 586.0) | < 0.001 |
CD8 T cell (× 106/L) | 380.0 (220.3, 474.5) | 310 (210.0, 423.5) | 0.114 |
CD4/ CD8 | 1.96 (1.31, 2.58) | 1.53 (1.31, 1.86) | 0.038 |
Hemoglobin (g/L) | 96.5 (80.0, 107.7) | 111.0 (100.7, 121.0) | < 0.001 |
Albumin (g/L) | 33 (31, 35) | 39 (38, 41) | < 0.001 |
Pre-albumin (g/L) | 0.33 (0.26, 0.38) | 0.31 (0.24, 0.4) | 0.402 |
Total cholesterol (mmol/L) | 4.3 (3.7, 5.1) | 4.1 (3.5, 4.7) | 0.265 |
Triglyceride (mmol/dl) | 1.3 (0.9, 2.2) | 1.4 (1.0, 2.3) | 0.285 |
ALT (U/L) | 12.0 (9.0, 18.7) | 6.0 (5.0, 9.2) | < 0.001 |
AST (U/L) | 14.0 (11.0, 19.7) | 19.0 (15.0, 27) | < 0.001 |
SCr (μmol/L) | 904 (679, 1149) | 991 (814, 1166) | 0.026 |
BUN (mmol/L) | 18.4 (15, 22.1) | 27.2 (21.8, 31.1) | < 0.001 |
Calcium (mmol/L) | 2.2 (2.1, 2.4) | 2.3 (2.2, 2.5) | 0.905 |
Phosphorus (mmol/L) | 1.6 (1.3, 1.9) | 2.3 (1.7, 2.6) | < 0.001 |
iPTH (pg/mL) | 137.0 (78.9, 273.9) | 263.5 (170.8, 384.2) | < 0.001 |
β2-MG (mg/L) | 27.1 (21.5, 37.7) | 39.1 (33.8, 43.5) | < 0.001 |
Iron (μmol/L) | 10.0 (7.3, 13.0) | 11.2 (8.9, 14.4) | < 0.001 |
Ferritin (μg/mL) | 274.3 (135.4, 463.7) | 301.8 (139.3, 494.0) | 0.841 |
IL-6 (pg/ml) | 6.3 (3.9, 11.0) | 9.9 (3.7, 65.7) | 0.014 |
TNF-α (pg/ml) | 17.2 (13.7, 21.2) | 30.0 (23.4, 61.4) | < 0.001 |
hsCRP (mg/L) | 3.1 (1.6, 9.5) | 3.9 (1.5, 8.0) | 0.564 |
WBC White blood cells, ALT Alanine aminotransferase, AST Aspartate aminotransferase, SCr Serum creatinine, BUN Blood urine nitrogen, β2-MG β2-microglobin, iPTH Parathyroid hormone, hsCRP high-sensitive C-reactive protein