Table 3.
Factors associated with MTB strains harboring inhA mutation in 2015
| Characteristics | No. of INH-resistant isolates (%) | P value | OR (95% CI) | |
|---|---|---|---|---|
| With inhA mutation (n = 28) |
Without inhA mutation (n = 77) |
|||
| Sex | ||||
| Men | 18(64.3) | 51(66.2) | 0.85 | 1.09(0.44–2.70) |
| Women | 10(35.7) | 26(33.8) | 1.00(Ref) | |
| Age group (years) | ||||
| <25 | 3(10.7) | 6(7.8) | 0.39 | 0.47(0.10–2.30) |
| 25–44 | 8(28.6) | 34(44.2) | 1.00(Ref) | |
| 45–64 | 12(42.9) | 27(35.1) | 0.22 | 0.53(0.19–1.48) |
| >64 | 5(17.9) | 10(13.0) | 0.29 | 0.47(0.13–1.76) |
| Treatment History | ||||
| New case | 16(35.7) | 47(79.2) | 1.00(Ref) | |
| Re-treated | 12(64.3) | 30(20.8) | 0.72 | 0.85(0.35–2.05) |
| Previous drug exposure | ||||
| INH | 12(77.8) | 30(26.0) | 0.72 | 0.85(0.35–2.05) |
| RIF | 12(77.8) | 30(26.0) | 0.72 | 0.85(0.35–2.05) |
| EMB | 12(77.8) | 30(26.0) | 0.72 | 0.85(0.35–2.05) |
| PZA | 12(77.8) | 30(26.0) | 0.72 | 0.85(0.35–2.05) |
| SLID | 8(32.1) | 19(15.6) | 0.69 | 0.82(0.31–2.16) |
| FQ | 10(39.3) | 22(20.8) | 0.48 | 0.72(0.29–1.80) |
| PTH | 6(21.4) | 4(5.2) | 0.02 | 0.20(0.05–0.78) |