Table 3.
References | SNP | Frequency of allele in elite endurance runners, % | Frequency of allele in controls, % |
P-value |
---|---|---|---|---|
Ahmetov et al., 2015 | NFIA-AS2 rs1572312 C TSHR rs7144481 C RBFOX1 rs7191721 G |
95.5 25.7 58.6 |
88.8 17.4 56.3 |
0.007* 0.032* 0 .60 |
Amir et al., 2007 | ACE D rs4646994 ACE DD rs4646994 |
77.0 62.0 |
66.0 43.0 |
0.01* 0.004* |
Ash et al., 2011 | ACE I/D rs4646994 ACE A22982G rs4363 |
44.7 44.7 |
45.6 45.8 |
0.16 0.97 |
Döring et al., 2010 | HIF1A Pro582 rs11549465 C HIF1A rs17099207 A HIF1A rs1951795 C HIF1A rs11158358 C/G HIF1A rs2301113 A/C HIF1A rs11549467 G/A |
84.0 9.2 67.7 25.3 33.5 3.2 |
75.0 4.9 62.2 27.0 32.9 1.6 |
0.017* 0.045* 0.038* 0.07 0.06 0.21 |
He et al., 2015 | PPARAGC1A rs4452416 T PPARAGC1B rs2161257 G NRF1 rs7794909 T SIRT1 rs11596401 C |
17.2 39.6 9.6 87.2 |
13.1 33.6 5.8 83.3 |
0.035* 0.026* 0.007* 0.050* |
Martinez et al., 2009 | AQP1 rs1049305 C | 57.0 | 49.0 | 0.03* |
Myerson et al., 1999 | ACE I rs4646994 | 52.0 | 49.0 | 0.01* |
Sawczuk et al., 2013 | ADRA2A rs553668 C | 85.8 | 82.9 | 0.40 |
Tobina et al., 2010 | ACE I/D rs4646994 | 44.0 | 44.0 | 0.001* |
Wolfarth et al., 2008 | NOS3 Glu298Asp rs1799983 G/T NOS3 (CA)n repeats 164 bp NOS3 27-bp repeats 4B/4A |
41.0 24.1 25.0 |
47.0 16.7 25.0 |
0.27 0.01* 0.83 |
*Significant difference between elite endurance, including marathon runners, and controls at p < 0.05 level.