Table 3.
Cost analysis of additional histopathological assessment of the terminal ileum for every Italian and United States (US) patient undergoing colonoscopy with multiple colorectal biopsies for chronic nonbloody diarrhea.
| Additional procedure | Workflow | Italian cost in Euros (€) | US cost in dollars ($) |
|---|---|---|---|
| Endoscopic sampling | Terminal ileum biopsies (two to four bites) placed in a separate disposable container preloaded with buffered formalin | 0.25 | 0.25 |
| Standard slide preparation | Specimen embedding, sectioning, hematoxylin and eosin staining | 10.00 | 12.00 |
| Pathology review | Reading, analysis and report drafting | 5.00 | 9.30 |
| Special situationsa | Specimens sectioned for two additional immunohistochemistry staining and pathology review | 30.00 | 50.00 |
| Total cost | 18.25 | 26.55 | |
a
Special situations occurred every 10 patients on average.