Table 3.
AMPs or effectors related to NF-κB pathways identified in shrimps.
| AMPs | Species | Types | Function identified | Signaling pathways | References |
|---|---|---|---|---|---|
| LvPEN2 | L. vannamei | Penaeidin | Anti-Vibrio | AP-1 (c-Fos, c-Jun) | (27, 119, 140) |
| LvPEN3 | L. vannamei | Penaeidin | Anti-Vibrio | Toll, AP-1 | (24, 27, 119, 140) |
| LvPEN4 | L. vannamei | Penaeidin | Anti-Vibrio | IMD; Toll2; NF-κB; AP-1 | (11, 12, 17, 27, 119, 140, 141) |
| LvCru1 | L. vannamei | Crustin | V. alginolyticus: down | Toll4; TAK1; IAP | (27, 112, 142, 143) |
| LvCru2 | L. vannamei | Crustin | ND | TAK1 | (112) |
| LvCru3 | L. vannamei | Crustin | ND | Toll4; TAK1; IAP | (27, 112, 143) |
| LvCrustinA | L. vannamei | Crustin | Anti-Vibrio; Anti-WSSV | NF-κB; AP-1 | (141) |
| LvCrustinP | L. vannamei | Crustin | ND | Toll; IMD; AP-1; NF-κB | (24, 144) |
| LvALF1 | L. vannamei | Anti-LPS-factor | Interact with VP19, VP26, VP28, wsv134, and wsv321 | IMD; Toll4; Dorsal | (24, 27) |
| LvALF2 | L. vannamei | Anti-LPS-factor | Anti-Vibrio; Anti-fungi; Anti-WSSV | Toll4; Dorsal | (27, 145) |
| LvALF3 | L. vannamei | Anti-LPS-factor | Anti-Vibrio; anti-WSSV | Toll4; Dorsal | (27) |
| LvCTL3 | L. vannamei | C-type lectin | Anti-Vibrio; anti-WSSV | Dorsal | (146) |
| LvCTL4 | L. vannamei | C-type lectin | Anti-Vibrio | NF-κB | (147) |
| LvLYZ1 | L. vannamei | Lysozyme | Anti-Vibrio; Anti-WSSV: Interact with VP26, VP28, wsv134, and wsv321 | Toll4; Dorsal; TAK1 | (27, 112) |
| LvLYZ2 | L. vannamei | Lysozyme | Anti-Vibrio; Anti-WSSV | Toll4; Dorsal; TAK1 | (27, 112) |
| LvLYZ3 | L. vannamei | Lysozyme | Anti-Vibrio; Anti-WSSV | Dorsal | (27) |
| LvLYZ4 | L. vannamei | Lysozyme | ND | Toll4; Dorsal; TAK1 | (27, 112) |
| LvTEP1 | L. vannamei | TEP | G+/G-: up; WSSV: up | NF-κB; AP-1 | (148) |
| FcPEN3 | F. chinensis | Penaeidin | ND | Relish | (149, 150) |
| FcPEN5 | F. chinensis | Penaeidin | Anti-bacteria | NF-κB | (13, 14, 151) |
| FcCru1 | F. chinensis | Crustin | ND | IMD; Relish | (109, 149, 152) |
| FcCru2 | F. chinensis | Crustin | ND | Spz | (41, 152) |
| FcCru3 | F. chinensis | Crustin | ND | IMD | (109, 152) |
| FcALF | F. chinensis | Anti-LPS-factor | ND | Relish | (149) |
| FcALF6 | F. chinensis | Anti-LPS-factor | ND | IMD | (109, 153) |
| FcALF8 | F. chinensis | Anti-LPS-factor | ND | IMD | (109) |
| FcLys2 | F. chinensis | Lysozyme | ND | IMD | (109) |
| PmPEN3 | P. monodon | Penaeidin | Anti-bacteria | Spz | (39, 154) |
| PmPEN411 | P. monodon | Penaeidin | ND | AP-1, Dorsal | (155) |
| PmPEN536 | P. monodon | Penaeidin | ND | AP-1, Dorsal | (119, 155) |
| PmPEN309 | P. monodon | Penaeidin | ND | Toll2 | (26) |
| Crus-likePm | P. monodon | Crustin | V. harveyi: up | NF-κB; STAT5; AP-1 | (26, 156) |
| crustinPm1 | P. monodon | Anti-LPS-factor | ND | Spz | (39) |
| crustinPm5 | P. monodon | Anti-LPS-factor | ND | NF-κB | (26, 157) |
| crustinPm7 | P. monodon | Anti-LPS-factor | ND | Spz | (39) |
| ALFPm2 | P. monodon | Anti-LPS-factor | V. harveyi: up | NF-κB; AP-1 | (158, 159) |
| ALFPm3 | P. monodon | Anti-LPS-factor | V. harveyi: up; WSSV: up | Spz | (39, 153, 158, 159) |
| MjLys1 | M. japonicas | Lysozyme | V. anguillarum: up; | Toll; IMD; Toll3 | (109, 160, 161) |
| Mj-Lys2 | M. japonicus | Lysozyme | ND | IMD | (109) |
| PcCru1 | P. clarkia | Crustin | V. anguillarum: up | Toll; IMD; Toll3 | (19, 36, 109) |
| PcCru2 | P. clarkia | Crustin | V. anguillarum: up | Toll; IMD | (19, 109) |
| PcALF1 | P. clarkii | Anti-LPS-factor | anti-bacteria | IMD; Toll4; Toll2; Toll3 | (35–37, 109, 162) |
| PcALF2 | P. clarkia | Anti-LPS-factor | V. anguillarum: up | IMD; Toll; Toll4; Toll2 | (19, 35, 37, 109) |
| PcALF4 | P. clarkia | Anti-LPS-factor | ND | Toll4 | (37) |
| PcALF7 | P. clarkia | Anti-LPS-factor | ND | Toll4 | (37) |
| PcALF10 | P. clarkia | Anti-LPS-factor | ND | Toll4 | (37) |
| PcLys1 | P. clarkii | Lysozyme | V. anguillarum: up; | Toll; IMD; Toll3 | (19, 36, 109) |
| MrCru2 | M. rosenbergii | Crustin | Anti-WSSV | Relish | (111) |
| MrCru3 | M. rosenbergii | Crustin | Anti-WSSV | Toll | (34) |
| MrCru5 | M. rosenbergii | Crustin | Anti-WSSV | Relish | (111) |
| MrCru7 | M. rosenbergii | Crustin | Anti-WSSV | Toll | (34) |
| MrCru8 | M. rosenbergii | Crustin | Anti-WSSV | Relish | (111) |
| MrALF2 | M. rosenbergii | Anti-LPS-factor | ND | Toll | (34) |
| MrALF3 | M. rosenbergii | Anti-LPS-factor | ND | Toll | (34) |
| MrALF4 | M. rosenbergii | Anti-LPS-factor | ND | Toll | (34) |
| MrALF5 | M. rosenbergii | Anti-LPS-factor | ND | Toll | (34) |
| MrLys1 | M. rosenbergii | Lysozyme | ND | Relish | (111) |
| MrLys2 | M. rosenbergii | Lysozyme | ND | Relish | (111) |
G+, Gram-positive bacteria; G−: Gram-negative bacteria; up, differentially up-regulated; down, differentially down-regulated; ND, Not determined.