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. 2019 Jul 30;7:176. doi: 10.3389/fbioe.2019.00176

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Copyright © 2019 Eltit, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Particles observed in periprosthetic tissues. (A–C) CoCrMo metal particles of sub-micron size group in leukocyte infiltrated areas (A); they show a high contrast in back-scattered electron image due to their high density (B); the EDS spectrum shows peaks of Co, Cr, and Mo (C). (D–F) chromium phosphate particles, tens to hundreds of microns in size usually surrounded by a collagenous capsule (D), showing low density in back scattered electron image (E), and peaks in Cr, O, and P in EDS spectrum (F).