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. 2019 Aug 2;11:7307–7315. doi: 10.2147/CMAR.S210545

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© 2019 Chai et al.

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LOX-1+ PMN is accumulated in GBM tissues and associated with early recurrence. (A, B) Double immune-fluorescent staining shows the LOX-1 expression (red), CD15 (green) and co-localization of double-positive cells (yellow) in 20 GBM patient tissue. Representative results are shown in (A). The density of LOX-1+ PMN in patients and healthy donor are shown in (B). (C) Association between LOX-1+ PMN and early recurrence. Using 6 months as the cutoff, 20 GBM patients were divided into two groups: recurrence (N=13) and no recurrence (N=7). ***P<0.001.

Abbreviations: LOX-1, lectin-type oxidized LDL receptor 1; PMN, polymorphonuclear neutrophil; GBM, glioblastoma multiforme.