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. Author manuscript; available in PMC: 2019 Aug 6.
Published in final edited form as: Hum Immunol. 2016 Aug 10;77(12):1147–1153. doi: 10.1016/j.humimm.2016.08.004

Fig. 2.

Fig. 2.

Impact of HLA-C expression on NK cell subset distribution and function among HIV-1 infected subjects. Predicted HLA-C expression levels are depicted based on individual HLA-C allotypes (A) and show differential levels among clinical subgroups including elite controllers (EC), n = 11; viremic controllers (VC), n = 8; chronic progressors (CRO), n = 10, healthy controls (HC), n = 154. Open shapes indicate subjects in the HLA-C1/C1 group, half-open shapes represent subjects in the HLA-C1/C2 group; and closed shapes represent subjects in the HLA-C2/C2. The flow plots illustrate the differences in NK cell subset distribution and IFN-γ secretion in subjects with low or high HLA-C expression (B). The differences in NK subset distribution and IFN-γ secretion are illustrated in subjects expressing KIR2DL1 and KIR2DL3 (C).