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. 2019 Aug 6;14(8):e0220029. doi: 10.1371/journal.pone.0220029

Table 2. Guidelines used in selecting LD50 values from multiple sources of data.

Rule Number Available LD50 Data Application
1 Single "exact" value reported Used unmodified in analysis
2 Single value reported but qualified as "approximate" or "greater than" (>) Used unmodified in analysis
3 Multiple "exact" values reported Arithmetic mean of all values used in analysis unless the difference between the lowest and highest values was greater than 10-fold and then the geometric mean is used
4 Multiple values reported but all qualified as "greater than" (>) Highest value used in analysis
5 Values reported but qualified as "less than" (<) Not used in analysis