Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 6;14(8):e0219940. doi: 10.1371/journal.pone.0219940

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Nair et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 4 — Immunofluorescence imaging showing the distribution of AQP2 in the kidney principal cells (PCs). Under baseline conditions, AQP2 localization in the cortical collecting duct (CCD) PCs is sex-independent in both WT and Atp6v1b1-/- (B1^-/-) mice. Upon dehydration AQP2 localization partially shifted towards the apical membrane. This effect was more pronounced in the male animals, of which B1^-/- mice showed the strongest response. Every panel has an average line intensity plot (black line) showing the distribution of protein within the cell. SD of the data is shown as a green area plot around the mean value plot. Peak intensity (I_peak) values and the total intensity distribution near the plasma membrane (A_mem) are also shown.