Table 1. Effect of dehydration on 12 h urinary excretion of Na, K, and Cl.
| WT M | WT M DH | WT FM | WT FM DH | B1-/- M | B1-/- M DH | B1-/- FM | B1-/- FM DH | |
|---|---|---|---|---|---|---|---|---|
| Na | 3.3±1 | 2.2±0.87* | 2.89±0.9 | 2.19±0.77* | 4.1±1.4 | 3.24±0.8 | 3.6±1 | 3±0.98 |
| K | 18.53±6.6 | 13.11±5.8 | 19.21±3.9 | 10.3±2.7*$ | 19.5±6.2 | 16.4±3.6 | 18.26±3.8 | 12.83±4.5 |
| Cl | 8.26±2.7 | 5.42±2.1 | 8.19±1.9 | 4.8±1.4* | 9.52±3.3 | 7.88±1.8 | 8.33±2.3 | 6.0±1.9 |
M–male, FM–Female, DH–Dehydrated. Values are expressed as mean ± SD (mg/12h), n = 6 for every data point. One-way ANOVA test followed by Tukey’s correction for multiple comparisons was conducted for statistical analysis.
*P < 0.05 compared to B1-/- M
$P < 0.05 compared to WT FM.