Table 2. Top five enriched functions for genes in cluster 1.
Category | Term ID | Term Description | q-value |
---|---|---|---|
GO-MF | GO:0008092 | cytoskeletal protein binding | 1.52E-07 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 1.28E-05 | |
GO:0030695 | GTPase regulator activity | 1.28E-05 | |
GO:0005088 | Ras guanyl-nucleotide exchange factor activity | 4.74E-05 | |
GO:0060589 | nucleoside-triphosphatase regulator activity | 7.98E-05 | |
GO-CC | GO:0045202 | synapse | 3.82E-34 |
GO:0097458 | neuron part | 1.99E-33 | |
GO:0043005 | neuron projection | 8.23E-28 | |
GO:0044456 | synapse part | 8.31E-28 | |
GO:0044463 | cell projection part | 4.65E-21 | |
GO-BP | GO:0098916 | anterograde trans-synaptic signaling | 1.94E-20 |
GO:0007268 | chemical synaptic transmission | 1.94E-20 | |
GO:0099537 | trans-synaptic signaling | 1.94E-20 | |
GO:0099536 | synaptic signaling | 3.04E-20 | |
GO:0032990 | cell part morphogenesis | 3.70E-18 | |
Pathway | 1268763 | Neuronal System | 2.01E-09 |
169346 | Regulation of RAC1 activity | 1.29E-06 | |
1268766 | Transmission across Chemical Synapses | 9.25E-06 | |
P00057 | Wnt signaling pathway | 1.34E-03 | |
1270303 | Axon guidance | 1.34E-03 | |
Diseases | C0036341 | Schizophrenia | 2.27E-09 |
C0005586 | Bipolar Disorder | 1.32E-07 | |
C3714756 | Intellectual Disability | 1.32E-07 | |
C0004352 | Autistic Disorder | 7.52E-06 | |
C0014544 | Epilepsy | 1.12E-05 |