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. 2019 Jul 25;15(7):e1008287. doi: 10.1371/journal.pgen.1008287

Fig 5. rs2355739-rs1194196 variants alter protein:DNA interactions.

Fig 5

(A) Electromobility shift assay using probes containing 70bp of genomic sequence containing SNPs rs2355739 and rs1194196. Digoxin-labeled Probes were incubated with K562 cell nuclear extract where indicated, resolved by gel electrophoresis, and imaged with anti-digoxin antibodies. Arrow indicated specific complex formed by protein:DNA interactions. (B) Quantification of DNA:protein complex by densitometry. (N = 3) Significance by one-sample T-test.