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. Author manuscript; available in PMC: 2019 Aug 6.
Published in final edited form as: Cancer Cell. 2019 Mar 18;35(3):347–367. doi: 10.1016/j.ccell.2019.01.007

Figure 3. Origin and Consequences of Integrin-Mediated Mechanotransduction in Cancer.

Figure 3.

Oncogenic signaling and changes in cell fate contribute to deregulate integrin expression and function in cancer. Changes in matrix composition and structure enable integrins to transmit integrated biochemical and mechanical signals to the interior of cancer cells.