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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Ann Epidemiol. 2019 Apr 3;34:33–39. doi: 10.1016/j.annepidem.2019.03.014

Table 3.

Hazard ratios (95% Confidence Intervals) for cancer of urinary system according to tea consumption in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study

Model adjustment Tea consumption (cups/day)1
Non-drinker <1 >1 P trend 1 cup/day increase
Bladder cancer
No. of cases/ person-years 553/297,629 223/132,968 59/42,441
Unadjusted model 1 0.88 (0.76–1.03) 0.73 (0.56–0.96) 0.02 0.90 (0.80–1.01)
Multivariable adjusted 1 0.91 (0.78–1.07) 0.77 (0.58–1.00) 0.046 0.92 (0.82–1.03)
Multivariable adjusted 1 0.92 (0.78–1.08) 0.77 (0.58–1.02) 0.07 0.92 (0.82–1.04)
Renal cell carcinoma
No. of cases/ person-years 226/292,468 109/130,788 31/42,678
Unadjusted model 1 1.07 (0.85–1.35) 0.96 (0.66–1.39) 0.86 0.99 (0.85–1.15)
Multivariable adjusted2 1 1.11 (0.88–1.40) 1.00 (0.68–1.46) 0.95 1.01 (0.86–1.17)
Multivariable adjusted3 1 1.10 (0.87–1.40) 0.97 (0.65–1.44) 0.92 0.99 (0.84–1.16)
1

One 8 oz cup=237 grams of tea

2

Adjusted for age (continuous), BMI (kg/m2, continuous), level of education (high school or less, greater than high school), years of smoking (continuous), cigarettes smoked per day (continuous), alcohol (grams/day, continuous), tea consumption (drinker, non-drinker), history of diabetes (yes or no), frequency of physical activity in leisure time (<1/week, 1–2/week, ≥3/week), Energy (kcal/day, continuous), nutrient density adjusted fruit consumption (grams/day, continuous), nutrient density adjusted vegetable consumption (grams/day, continuous)

3

Additionally adjusted for coffee consumption (cups/day)