Table IV.

Description of the sample of children with measured proteins (n = 812)

	Overall n	Neurotrophic risk group* (proteins included in top quartile)			No. of elevated neurotrophic proteins†
		1: None (n = 552)	2: RANTES, BDNF, ANG-1 (n = 133)	3: >3—not RANTES, BDNF, ANG-1 (n = 127)	0–1 (n = 395)	2–3 (n = 232)	≥4 (n = 185)
Maternal characteristics
Racial identity
White	505	62	68	62	63	59	68
Black	208	27	19	27	26	31	20
Other	90	11	13	10	11	10	12
Hispanic
Yes	80	10	14	7	9	9	11
No	731	90	86	93	91	91	89
Body mass index
Under	64	8	7	11	9	6	10
Normal	390	49	52	50	49	50	51
Over	152	20	22	13	22	16	19
Obese	179	23	20	26	21	29	20
Education, years
≤12	322	40	43	40	41	38	45
>12, <16	185	24	22	24	22	27	22
≥16	283	36	35	36	38	35	33
Marital status, single
Yes	329	40	37	47	38	43	42
No	483	60	63	53	62	57	58
Public insurance
Yes	286	36	31	37	37	33	34
No	526	64	69	63	63	67	66
Cigarette exposure in pregnancy
None	567	73	68	68	74	70	67
Passive	120	14	16	20	14	15	18
Smoker	108	13	16	12	12	15	14
Newborn characteristics
Sex
Male	413	51	47	55	51	53	48
Female	399	49	53	45	49	47	52
Gestational age, weeks
23–24	173	21	20	24	21	24	20
25–26	366	44	46	48	45	44	46
27	273	35	35	28	35	32	34
Birth weight z-score
<−2	49	7	2	8	6	6	6
≥−2, <−1	106	12	11	19	11	16	14
≥−1	657	81	87	73	82	79	81
Inflammatory proteins
IRG1	634	87	65	51
IRG2	130	11	23	32
IRG3	48	2	12	17
Inflammatory proteins
0–1	540				85	59	38
2–3	164				11	27	30
≥4	108				4	14	32

^*No significant differences in characteristics by neurotrophic risk group except for birth weight z-score (P = .043) and inflammatory proteins (P < .001).

^†No significant differences in characteristics by number of neurotrophic proteins except for inflammatory proteins (P < .001).