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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Clin Trials. 2018 Oct 11;16(1):32–40. doi: 10.1177/1740774518801599

Table 2.

Within trial dose allocation

Patient Group d1max d2max d3max Dose allocated DLT
1 3 (most frail) - - - 1 no
2 2 (less frail) - - 1 2 no
3 2 (less frail) - 2 1 3 no
4 3 (most frail) - 3 1 2 no
5 1 (less frail) - 3 2 4 yes

End stage 1. Begin stage 2 modeling.