TABLE 3.

Alcohol and cannabis users at baseline and clinical characteristics during 24-mo treatment (Beta’s, confidence intervals and P values)

Clinical characteristics	Alcohol users			Cannabis users			Tobacco smokers
	β	95% CI	P value	β	95% CI value	P value	β	95% CI	P value
PANSS total	NS			NS			4.43	1.68 to 7.17	<.01
PANSS negative	NS			NS			1.30	0.12 to 2.48	<.05
PANSS positive	NS			1.56	0.31–2.81	<.05	1.53	0.38 to 2.69	<.01
PANSS disorganized thought	NS			NS			NS
PANSS hostility	NS			NS			0.59	0.20 to 0.99	<.01
PANSS depression	NS			NS			NS
QoL total mean score	NS			NS			−0.31	−0.53 to −0.09	<.01
QOL interpersonal relations	NS			NS			NS
QOL instrumental	NS			NS			−0.56	−0.93 to −0.19	<.01
QOL intrapsychic	NS			NS			−0.34	0.55 to −0.13	<.01
QOL common objects activities	NS			NS			−0.25	−0.48 to −0.01	<.05
Missed medications	3.16	0.31–6.01	P < .05	NS			2.89	0.32 to 5.48	<.05
CGI severity	NS			0.18	0.01–0.36	<.05	0.24	0.07 to 0.40	<.005

	Treatment group			DUP
Clinical characteristics	Β	95% CI	P value	β	95% CI	P value
PANSS total	NS			7.56	−4.85 to 10.28	<.001
PANSS negative	NS			1.31	0.18 to 2.44	<.05
PANSS positive	NS			2.87	1.73 to 4.02	<.001
Disorganized thought	NS			NS
PANSS hostility	NS			0.76	0.34 to 1.18	<.001
PANSS Depression	NS			NS
QoL total	NS			0.33	−0.54 to −0.13	<.01
Interpersonal relations	NS			NS
Instrumental	NS			NS
Intrapsychic	NS			−0.24	−0.44 to −0.03	<.05
Common objects activities	NS			NS
Missed medications	6.35	3.71–8.99	<0.001	NS
CGI severity	NS			0.46	0.30 to 0.62	<.001