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Reactivity of antistreptococcal/antimyosin mAb 3.B6 with normal human valve endothelium and myocardium. Formalin-fixed human mitral valve (A) and myocardium (B) were reacted with mAb 3.B6 at 10 μg/ml. mAb 3.B6 binding was detected using biotin-conjugated antihuman antibodies and alkaline phosphatase-labeled streptavidin followed by fast red substrate. Control sections did not react with human IgM at 10 μg/ml (C,D). (Reproduced with permission from Lippincott Williams and Wilkins).
