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. 2019 Aug 2;7(4):10.1128/microbiolspec.gpp3-0045-2018. doi: 10.1128/microbiolspec.gpp3-0045-2018

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Antimyosin antibody cross-reactive sites in M5 protein A, B, and C repeat regions of the molecule. Arrows point to sites determined to induce human cardiac myosin cross-reactive antibody (32). The asterisk (*) marks the location of peptide NT4 containing several repeats of an epitope in cardiac myosins that causes myocarditis in MRL/++ and BALB/c mouse strains (32, 116). Site QKSKQ is the epitope determined to react with antimyosin antibody in ARF sera (40). (Reproduced from Effects of Microbes on the Immune System with permission from Lippincott Williams and Wilkins.)