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Sequence homology between human cardiac myosin and peptide NT4 that causes myocarditis (32, 119). The homologous sequence repeats four times in the streptococcal M5 protein and in NT4 and once in cardiac myosin. Repeated sequences in M proteins that mimic cardiac myosin may be important in inducing inflammatory heart disease. (Adapted from reference 119 with permission from the Journal of Immunology.)
