Skip to main content
. Author manuscript; available in PMC: 2020 May 28.
Published in final edited form as: J Control Release. 2019 Apr 8;302:181–189. doi: 10.1016/j.jconrel.2019.04.009

Fig. 2. C3 opsonization of SPIO NWs is inhibited by SCR-2-3-4.

Fig. 2

A) a schematic representation of procedures for measuring C3 deposition on SPIO NWs; B) SPIO NWs were incubated in human plasma and washed of excess proteins. Bound C3 was analyzed with SDS-PAGE. Lane labels: 1) C3b; 2) iC3b; 3) no inhibitor; 4) 20 mM EDTA; 5) 81.5 nM SCR-2-3-4; 6) 410 nM SCR-2-3-4; 7) 815 nM SCR-2-3-4; 8) 4100 nM SCR-2-3-4. The experiment was done in 3 different plasma donors [legends show gender (f/m) and age (number) of each donor]. Individual data points of 3 technical replicates for each donor are shown.