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. Author manuscript; available in PMC: 2019 Aug 6.
Published in final edited form as: Dev Psychopathol. 2018 Dec;30(5):1729–1747. doi: 10.1017/S095457941800127X

Table 3.

Testing polygenic moderation of intervention effects on Total Symptoms

Est. SE P Lower CI Upper CI R2

Polygenic Score (p = .05)
Gender −2.268 1.253 .070 −4.723 .187 .033
Age −.076 .208 .716 −.484 .332
Income −.040 .676 .953 −1.364 1.285
Site 1 −.484 1.657 .770 −3.731 2.763
Site 2 −.763 1.671 .648 −4.037 2.512
PC1 .748 .755 .322 −.732 2.227
PC2 .184 .634 .772 −1.059 1.426
Intervention −1.093 1.236 .377 −3.516 1.330
Polygenic Score 2.066* .891 .020 .319 3.813
Polygenic X Intervention −3.261** 1.237 .008 −5.685 −.836

Polygenic Score (p = .10)

Gender −2.165 1.257 .085 −4.629 .298 .028
Age −.095 .209 .648 −.504 .314
Income −.098 .678 .885 −1.427 1.230
Site 1 −.263 1.675 .875 −3.546 3.021
Site 2 −.674 1.678 .688 −3.963 2.615
PC1 .744 .782 .341 −.788 2.276
PC2 .188 .636 .767 −1.059 1.436
Intervention −1.156 1.240 .351 −3.586 1.274
Polygenic Score 1.466 .901 .104 −.300 3.232
Polygenic X Intervention −2.670* 1.229 .030 −5.080 −.260