Table 4.
Regions of significance and simple slopes for significant interactions
| Regions of Significance for the Polygenic Score | Simple Slopes for the Polygenic Score by Intervention Status | ||||
|---|---|---|---|---|---|
| Lower Bound | Upper Bound | Control | Intervention | ||
| Polygenic Score (p = .05) | Total Symptoms General Anxiety | −2.019 | .493 | 2.066* (.891) | −1.195 (.865) |
| General Anxiety | −1.941 | .494 | .403** (.159) | −.186 (.154) | |
| Obsessive Compulsive Symptoms | −1.015 | 1.847 | .248** (.090) | −.052 (.086) | |
| Manic Symptoms | −1.031 | .934 | .391* (.170) | −.271 (.165) | |
| Polygenic Score (p = .10) | Total Symptoms | −5.380 | .660 | 1.466 (.901) | −1.204 (.894 |
| General Anxiety | −2.161 | .501 | .371* (.160) | −.197 (.159) | |
| Obsessive Compulsive Symptoms | −.970 | 1.669 | .240** (.090) | −.067 (.089) | |
| Manic Symptoms | −4.088 | 2.497 | .112 (.172) | −.371* (.171) | |
Note. Polygenic risk scores were Z-scored, so regions of significance are on a metric of standard deviations above and below the mean. The control and intervention groups are significantly different outside the upper and lower bounds of the region of significance for all models.