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. Author manuscript; available in PMC: 2020 Aug 6.
Published in final edited form as: J Am Coll Cardiol. 2019 Aug 6;74(5):659–668. doi: 10.1016/j.jacc.2019.05.060

Central Illustration: Methylprednisolone Therapy in Neonates Undergoing Cardiac Operations with Cardiopulmonary Bypass and Morbidity-Mortality.

Central Illustration:

Forest plots of primary and subgroup analyses of methylprednisolone and the morbidity-mortality composite outcome. Methylprednisolone failed to show an overall benefit but there may be center or patient characteristics which make prophylactic methylprednisolone beneficial.