Table 1.
Baseline characteristics of 194 women with HIV according to treatment assignment.
| Baseline Characteristics | Total (N=194) |
Naltrexone (n=96) |
Placebo (n=98) |
|---|---|---|---|
| SOCIO-DEMOGRAPHICS | |||
| Age (Mean ± SD) | 48 ± 9 | 48 ± 8 | 49 ± 9 |
| Age group | |||
| 18–39 | 29 (15%) | 16 (17%) | 13 (13%) |
| 40–49 | 67 (35%) | 35 (36%) | 32 (33%) |
| 50–59 | 80 (41%) | 37 (39%) | 43 (44%) |
| ≥60 | 18 (9%) | 8 (8%) | 10 (10%) |
| Race/Ethnicity | |||
| Hispanic | 22 (11%) | 11 (11%) | 11 (11%) |
| Not Hispanic, White | 8 (4%) | 3 (3%) | 5 (5%) |
| Not Hispanic, Black | 161 (83%) | 81 (84%) | 80 (82%) |
| Not Hispanic, Other | 3 (2%) | 1 (1%) | 2 (2%) |
| Married or in a long-term relationship | 31 (16%) | 16 (17%) | 15 (15%) |
| Employed | 20 (10%) | 11 (11%) | 9 (9%) |
| Education | |||
| Less than high school | 84 (43%) | 40 (42%) | 44 (45%) |
| High school graduate | 66 (34%) | 38 (40%) | 28 (29%) |
| Some college or college graduate | 44 (23%) | 18 (19%) | 26 (27%) |
| ALCOHOL CONSUMPTION | |||
| Number of standard drinks per week (Mean ± SD) | 66 ± 78 | 58 ± 51 | 73 ± 97 |
| Abstinent days in the past 30 days (Mean ± SD) | 9 ± 8 | 8 ± 8 | 9 ± 8 |
| Binge drinking days in the past 30 days (Mean ± SD) | 18 ± 9 | 19 ± 9 | 18 ± 10 |
| Alcohol craving score (Mean ± SD) | 5.9 ± 2.9 | 6.0 ± 3.0 | 5.8 ± 2.7 |
| SIP score (Mean ± SD) | 12.9 ± 11.1 | 13.1 ± 11.4 | 12.7 ± 10.9 |
| AUDIT score (Mean ± SD) | 17 ± 8 | 17 ± 8 | 16 ± 8 |
| Alcohol use disorder | |||
| No | 74 (38%) | 28 (29%) | 46 (47%)* |
| Alcohol abuse only | 16 (8%) | 11 (12%) | 5 (5%) |
| Alcohol dependence | 103 (53) | 56 (59%) | 47 (48%) |
| PEth value | |||
| <8 ng/mL | 102 (53%) | 49 (51%) | 53 (54%) |
| 8–20 ng/mL | 18 (9%) | 10 (10%) | 8 (8%) |
| >20 ng/mL | 74 (38%) | 37 (39%) | 37 (38%) |
| HIV CLINICAL AND OTHER BEHAVIORAL FACTORS | |||
| HIV viral suppression (<200 copies/mL) | 119 (63%) | 57 (61%) | 62 (65%) |
| CD4 count (Mean ± SD) | 556 ± 346 | 541 ± 295 | 571 ± 391 |
| Currently on ART | 182 (94%) | 91 (95%) | 91 (93%) |
| ≥95% ART adherence in the past 30 daysa | 98 (61%) | 47 (59%) | 51 (63%) |
| BSI grand total score (Mean ± SD) | 28.6 ± 32.4 | 27.4 ± 32.6 | 29.7 ± 32.2 |
| Tobacco use in the past 30 days | 120 (63%) | 61 (64%) | 59 (61%) |
| Any drug use in the past 30 days | 109 (58%) | 56 (59%) | 53 (58%) |
| Risky sexual behavior in the past 12 months | 13 (7%) | 7 (7%) | 6 (6%) |
SD = Standard deviation, BSI = Brief Symptom Inventory
a
Among participants who were currently on ART
*
p < .05 by chi-square test