. Author manuscript; available in PMC: 2020 Aug 1.

Published in final edited form as: Alcohol Clin Exp Res. 2019 Jul 10;43(8):1790–1800. doi: 10.1111/acer.14130

Table 3.

Impact of naltrexone on 4-month unhealthy alcohol use: Subgroup analyses.

	Quit or reduced drinking (%)
	Naltrexone (n=85)	Placebo (n=87)	p value^*
Alcohol dependence
Yes (n=92)	28 (56%)	14 (33%)	.03
No (n=79)	16 (47%)	25 (56%)	.45
PEth value
Positive, ≥8 ng/mL (n=80)	19 (46%)	13 (33%)	.24
Negative, <8 ng/mL (n=92)	25 (57%)	26 (54%)	.80
Adherence to study medication
≥90% (n=112)	26 (52%)	27 (44%)	.37
<90% (n=58)	18 (53%)	11 (46%)	.59
Age
<50 years old (n=88)	19 (49%)	24 (53%)	.67
≥50 years old (n=84)	25 (54%)	15 (36%)	.08

p value from bivariate logistic regression within each subgroup