A, Representative examples of increases in [Ca2+]i produced by LPI in the absence/presence of the PLC inhibitor, U-73122 (10 μM), of L-type Ca2+ channel blocker, nifedipine (1 μM), and in Ca2+-free saline. B, Comparison of the amplitude of the average increase in [Ca2+]i elicited by LPI in each of the conditions mentioned; U-73122 did not affect the amplitude of LPI-induced increase in [Ca2+]i, while nifedipine or Ca2+-free saline abolished the response to LPI. (*P < 0.05; NS – not significant).