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. Author manuscript; available in PMC: 2020 Aug 15.
Published in final edited form as: J Immunol. 2019 Jul 8;203(4):899–910. doi: 10.4049/jimmunol.1801649

Figure 7. Early PD-1 expression during acute SIV infection predicts clinical outcomes of body weight and CD4+ T cell counts.

Figure 7.

To investigate the impact of PD-1 expression pre- and post-treatment on subsequent clinical outcomes, linear regression was used to test for associations between the frequencies of PD-1+ T cells in CD4+ T cells (upper panels) and CD8+ T cells (lower panels) at timepoints −2 weeks (pre-treatment baseline), 4 weeks (end of treatment) and 8 weeks p.i. vs. the clinical outcome variables of body weight (A) and CD4+ T cell counts (B) at 48 weeks p.i. Spearman r and p values are indicated in each panel. KMOi-treated animals are indicated in black and control animals in grey.