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. 2019 Aug 6;2:294. doi: 10.1038/s42003-019-0545-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — AMR class abundance for the shotgun metagenomic dataset of Noyes et al.³². Alignment (green), Meta-MARC HTS (orange), Meta-MARC Assembly (blue) and Resfams (purple) are compared. Meta-MARC Assembly identified the greatest number of reads in 11 out of 13 resistance classes. For the aminoglycosides and multi-drug resistance genes, Resfams identified a greater number of reads with Meta-MARC containing the second largest number of identifications in those classes. Overall, Meta-MARC Assembly detected 42-fold more reads than Alignment, and 1.5-fold more reads than Resfams