Fig. 3.

Angptl8 resets liver clock in vitro. a Representative luminescence traces of Per2::Luc U2OS cells stimulated with either Angptl8 or 50% horse serum for 2 h. b, c The periods and amplitudes of circadian transcriptional activities of Per2 promoter in Per2::Luc U2OS cells stimulated with either 40 nM Angptl8 or 50% horse serum for 2 h. n = 3. All the data were calculated from fit curve data. d qPCR analyses of time-course expression of clock genes in mouse Hepa1c1c-7 cells similarly treated in panel a. n = 3. All data are presented as the means ± SD. Source data are provided as a Source Data file