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. 2019 Jul 31;7:186. doi: 10.3389/fbioe.2019.00186

Figure 4.

Figure 4

Examples of LoC systems for the detection of bacteria. (A) Schematics of the device proposed by Choi et al. Adapted from Choi et al. (2006); (B) Final device proposed by Duarte et al. with the MR chip bonded to the polydimethylsiloxane (PDMS) microchannels (i); Sensor layout showing the distribution of the Spin-valve sensors along the microchannels (ii) and a photograph showing a representative microchannel aligned over the sensors (iii). Adapted from Duarte et al. (2016); (C) 3D paper-based microfluidic proposed by Choi et al. Reprinted with permission from Choi et al. (2016). Copyright 2016 Royal Society of Chemistry; (D) Monolithic device proposed by Dimov et al. (inset A) and schematics showing the different unitary operations occurring inside the device (inset B). Adapted with permission from Dimov et al. (2008). Copyright 2008 Royal Society of Chemistry; (E) Scheme of the LoC device proposed by Kim et al. Adapted with permission from Kim et al. (2014). Copyright 2014 American Chemical Society.