Table 6.
Predictors of nonadherence in patients with inflammatory bowel disease
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| Variables | Adherence rates | P value | Odds ratio | Odds ratio (95% CI) | P value |
| Gender | 0.348 | — | — | — | |
| Male (n = 142) | 114 (80.2) | ||||
| Female (n = 124) | 105 (84.6) | ||||
| Disease activity | 0.599 | — | — | — | |
| Remission (n = 155) | 126 (81.3) | ||||
| Active disease (n = 111) | 93 (83.8) | ||||
| Disease duration (years) | 8.5 ± 5.3 versus 5.9 ± 5.1 | 0.002 | 1.1 (1.02–1.14) | 1.2 (1.03–1.3) | 0.009 |
| Patient's education, n (%)† | <0.001 | — | — | — | |
| Professional or honors (n = 30) | 19 (63.3) | ||||
| Graduate or postgraduate (n = 77) | 66 (85.7) | ||||
| Intermediate or posthigh school diploma/high school certificate (n = 86) | 77 (89.5) | ||||
| Middle school certificate/primary school certificate (n = 47) | 32 (68.1) | ||||
| Illiterate (n = 26) | 25 (96.2) | ||||
| Patient's occupation, n (%)† | 0.097 | — | — | — | |
| Profession/semiprofession (n = 38) | 26 (68.4) | ||||
| Clerical, shop owner, farmer (n = 55) | 46 (83.6) | ||||
| Skilled worker/semiskilled worker/unskilled worker (n = 49) | 43 (87.8) | ||||
| Unemployed (n = 124) | 104 (83.9) | ||||
| Socioeconomic status, n (%)† | 0.021 | — | — | — | |
| Upper (n = 26) | 16 (61.5) | ||||
| Upper middle (n = 114) | 100 (87.7) | ||||
| Lower middle (n = 66) | 55 (83.3) | ||||
| Upper lower (n = 58) | 47 (81.0) | ||||
| Lower (n = 2) | 1 (50.0) | ||||
| Combined educational, occupational, and socioeconomic categories | <0.001 | 8.0 (2.6–25.1) | 17.6 (3.8–80.7) | <0.001 | |
| Group A (n = 17) | 8 (47) | ||||
| Group B (n = 69) | 60 (87) | ||||
| Group C (n = 8) | 8 (100) | ||||
| Steroids intake | 0.019 | 3.9 (1.2–13.2) | 4.03 (0.5–33.9) | 0.200 | |
| Yes (n = 49) | 46 (93.9) | ||||
| No (n = 217) | 173 (79.7) | ||||
| 5‐ASA intake | 0.061 | 2.5 (0.9–6.6) | 6.08 (0.5–70.6) | 0.149 | |
| Yes (n = 211) | 169 (80.1) | ||||
| No (n = 55) | 50 (90.9) | ||||
| Topical therapy | <0.001 | 3.8 (1.9–7.2) | 2.03 (0.5–8.2) | 0.320 | |
| Yes (n = 95) | 66 (69.5) | ||||
| No (n = 171) | 153 (89.5) | ||||
| Immunomodulators | 0.027 | 2.2 (1.1–4.4) | 5.3 (0.9–25.0) | 0.069 | |
| Yes (n = 106) | 94 (88.7) | ||||
| No (n = 160) | 125 (78.1) | ||||
Patient education, occupation, and socioeconomic status were not included in the multivariate analysis because they had collinearity with combined educational, occupational, and socioeconomic categories.
Group A: education: professional; occupation: professional; socioeconomic status: upper.
Group B: education: graduate‐postgraduate/intermediate or posthigh school diploma/high school certificate/middle school certificate/primary school certificate; occupation: clerical, shop owner, farmer/skilled worker/semiskilled worker/unskilled worker; socioeconomic status: upper middle and lower middle.
Group C: education: illiterate; occupation: unemployed; socioeconomic status: upper lower and lower.
5‐ASA, 5‐aminosalicylic acid; CI, confidence interval.