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. 2019 Jul 19;14(4):441–451. doi: 10.1007/s11523-019-00656-2

Table 3.

Diagnostic performance of change of plasma biomarkers from baseline to discriminate patients with and without (suspected) interstitial lung disease (ILD)

Plasma biomarker Median ratio for patients without (suspected) ILD (n = 13) Median ratio for patients with (suspected) ILD (n = 12) p value Area under the ROC curve Sensitivity Specificity Positive predictive value Negative predictive value
YKL-40 0.94 1.31 0.039 0.75 0.83 0.62 0.67 0.80
SP-D 0.64 1.27 0.003 0.85 0.83 0.85 0.83 0.85
SP-A 1.07 1.63 0.077 0.71
Uteroglobin 1.23 1.29 0.849 0.53
CCL18 0.27 0.38 0.231 0.64
CA 15.3 1.19 1.02 0.479 0.59
LDH 1.37 1.47 0.735 0.55

ROC receiver-operating characteristic