Table 3.
Plasma biomarker | Median ratio for patients without (suspected) ILD (n = 13) | Median ratio for patients with (suspected) ILD (n = 12) | p value | Area under the ROC curve | Sensitivity | Specificity | Positive predictive value | Negative predictive value |
---|---|---|---|---|---|---|---|---|
YKL-40 | 0.94 | 1.31 | 0.039 | 0.75 | 0.83 | 0.62 | 0.67 | 0.80 |
SP-D | 0.64 | 1.27 | 0.003 | 0.85 | 0.83 | 0.85 | 0.83 | 0.85 |
SP-A | 1.07 | 1.63 | 0.077 | 0.71 | ||||
Uteroglobin | 1.23 | 1.29 | 0.849 | 0.53 | ||||
CCL18 | 0.27 | 0.38 | 0.231 | 0.64 | ||||
CA 15.3 | 1.19 | 1.02 | 0.479 | 0.59 | ||||
LDH | 1.37 | 1.47 | 0.735 | 0.55 |
ROC receiver-operating characteristic