Table 5.

Longitudinal changes from baseline to one year within group for normal control, early AMD, and intermediate AMD patients. P-values are calculated to assess for significant change within each group over one year using the Wilcoxon signed-rank test.

Test	Statistic	Normal Control	Early AMD	Intermediate AMD
BCVA	N	19	27	39
	Mean (SD)	−1.3 (5.2)	1.0 (4.7)	−1.6 (6.8)
	Min, Median, Max	−15.0, −2.0, 6.0	−9.0, 1.0, 15.0	−15.0, −3.0, 25.0
	P-value	0.497	0.420	0.033
LLVA	N	19	27	39
	Mean (SD)	0.9 (5.1)	−0.4 (5.6)	−2.2 (7.5)
	Min, Median, Max	−12.0, 2.0, 8.0	−16.0, 0.0, 9.0	−24.0, −1.0, 12.0
	P-value	0.336	0.937	0.098
LLD	N	19	27	39
	Mean (SD)	−2.2 (5.8)	1.4 (5.4)	0.6 (7.1)
	Min, Median, Max	−16.0, −2.0, 9.0	−8.0, 1.0, 13.0	−14.0, 0.0, 15.0
	P-value	0.135	0.232	0.563
Microperimetry PRT (%)	N	18	25	35
	Mean (SD)	13.7 (20.5)	10.0 (35.0)	25.2 (27.4)
	Min, Median, Max	−18.9, 8.1, 62.2	−75.7, 8.1, 73.0	−18.9, 18.9, 94.6
	P-value	0.003	0.125	<0.001
Microperimetry AT (dB)	N	18	25	35
	Mean (SD)	−1.5 (1.7)	−1.4 (2.7)	−3.0 (3.3)
	Min, Median, Max	−4.5, −0.9, 1.2	−6.1, −2.1, 4.6	−18.5, −2.6, 1.2
	P-value	0.002	0.017	<0.001
CCT Red (%)	N	18	27	38
	Mean (SD)	−7.5 (17.8)	−1.3 (11.0)	−8.3 (12.7)
	Min, Median, Max	−40.0, −5.0, 20.0	−30.0, 0.0, 25.0	−45.0, −10.0, 20.0
	P-value	0.104	0.619	<0.001
CCT Green (%)	N	18	27	38
	Mean (SD)	−6.7 (11.4)	−3.7 (10.1)	−6.7 (15.1)
	Min, Median, Max	−35.0, −5.0, 15.0	−30.0, −5.0, 20.0	−50.0, −5.0, 20.0
	P-value	0.019	0.068	0.011
CCT Blue (%)	N	18	27	38
	Mean (SD)	−5.0 (13.6)	−0.7 (17.4)	−11.5 (15.4)
	Min, Median, Max	−30.0, −5.0, 25.0	−35.0, 0.0, 40.0	−45.0, −10.0, 30.0
	P-value	0.148	0.802	<0.001